Michael Chiklis
Slade Wilson / Deathstroke (voice)
Sasha Alexander
Adeline 'Addie' Kane Wilson (voice)
Chris Jai Alex
Jackal (voice)
Faye Mata
H.I.V.E. Queen / Jade (voice)
Griffin Puatu
Joseph Wilson / Jericho (voice)
Asher Bishop
Young Joseph Wilson (voice)
Imari Williams
President Nicholas / H.I.V.E. Pilot (voice)
Colin Salmon
William Wintergreen (voice)
Panta Mosleh
Lady Shiva / Nurse (voice)
Noshir Dalal
Kapoor / Doctor 2 (voice)